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Semaglutide exposure is dose proportionate in the PIONEER and SUSTAIN
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Efficacy and safety of oral semaglutide in patients with type 2 diabetes and moderate renal impairment (PIONEER 5): a placebo-controlled, randomised, phase 3a trial
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The PIONEER program tested oral semaglutide — the first GLP-1 receptor agonist available as a pill rather than injection. Across multiple PIONEER trials in T2DM, oral semaglutide produced HbA1c and weight reductions
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Efficacy and safety of oral semaglutide by subgroups of patient characteristics in the PIONEER phase 3 programme
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Dose-response, efficacy, and safety of oral semaglutide monotherapy in Japanese patients with type 2 diabetes (PIONEER 9): a 52-week, phase 2/3a, randomised, controlled trial
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![Composite primary outcome in PIONEER 6 [25]. Cumulative incidence plots...](https://www.researchgate.net/publication/343772424/figure/fig1/AS:1024481283817472@1621266780897/Composite-primary-outcome-in-PIONEER-6-25-Cumulative-incidence-plots-for-the-primary.png)
Composite primary outcome in PIONEER 6 [25]. Cumulative incidence plots...
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